P-Glycoprotein Antikörper (Center)
Kurzübersicht für P-Glycoprotein Antikörper (Center) (ABIN2794800)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 647-677, Center
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Verwendungszweck
- Rabbit Anti-Human P-Glycoprotein (ABCB1) (Center) Antibody
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Immunogen
- This P-Glycoprotein (ABCB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 647-677 amino acids from the Central region of human P-Glycoprotein (ABCB1).
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Isotyp
- Ig Fraction
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anti-P-Glycoprotein antibody
Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-P-Glycoprotein antibodyReaktivität: Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-P-Glycoprotein antibodyReaktivität: Human WB, FACS, IP Wirt: Maus Monoclonal 17F9 unconjugated
anti-P-Glycoprotein (AA 647-677) antibodyReaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-P-Glycoprotein antibodyReaktivität: Human, Hamster WB, IHC, FACS, ICC Wirt: Maus Monoclonal JSB-1 unconjugated
anti-P-Glycoprotein (AA 647-677) antibodyReaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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Western Blot
Recommended Dilutions
WB: 1:1000ABCB1 Antibody (L661) . -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 2.000 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- P-Glycoprotein
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Hintergrund
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Target Description: The membrane-associated ABCB1 protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. ABCB1 is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
Gene Symbol: ABCB1
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Molekulargewicht
- 141479 Da
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Gen-ID
- 5243
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UniProt
- P08183
Target
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